With a good map, boots that fit and plenty of food & water you really can't go wrong. The Southern Winds are famous for the Cirque of the Towers and the countless back country climbing routes that are found not only in the Cirque, but also on lesser known peaks such as Haystack, the Steeple Peaks and the Cathedral Cirques. Equally popular are backpacking excursions to Big Sandy Lake, the Stough Creek Basin, Wind River Peak and many others.
Wind River Range South by Beartooth Publishing
This trail map of the Southern Wind River Range is an excellent companion for your hiking and backpacking adventures in the Southern Wind River Range of Wyoming.